@article { orvium-630e34ad5c691ed692fbfc69, title = "Ibogaine and Cardiac Arrhythmia: The Heart of the Matter", abstract = "Even at therapeutic doses, ibogaine may cause potentially life-threatening cardiac arrhythmia. Science is beginning to unravel the pharmacological factors that may underlie ibogaine-induced cardiotoxicity.-Ibogaine has shown promising anti-addictive effects in both animal models and human trials, aiding those in search of a novel treatment for addiction and the compulsive behaviors that accompany it. One study found that 91.7% of opioid or cocaine-dependent participants felt ibogaine was useful in addressing substance abuse issues. 1 Despite ibogaine's demonstrated efficaciousness and mainstream acclaim, literature regarding its potential to induce potentially fatal heart arrhythmias and case reports on ibogaine-associated fatalities are accumulating as its pharmacology is further studied.", keywords = "Pharmacology, Toxicology, Electrophysiology, Clinical pharmacology, Ibogaine, arrhythmias, Etiology", author = "Christopher Teske", year = "2022", language = "English", url = "https://dapp.orvium.io/deposits/630e34ad5c691ed692fbfc69/view", }