@article {
    orvium-652e61ac47b4be402d9993f6,
    title = "THE EFFECT OF METHANOL EXTRACT OF PUERARIA PHASEOLOIDES (KUDZU ROOT) ON THE SPERM PARAMETERS OF WISTAR RATS",
    abstract = "The effects of oral administration of pueraria phaseoloides on the
reproductive characteristics of male wistar rats for 53 days were investigated
in this research. The experimental animals were randomly sorted into three
groups (two test groups and one control group) of four rats each.
The two test groups were orally administered 384µg/g/d and 1536µg/g/d of the
crude extract of the plant (pueraria phaseoloides) respectively on a daily basis.
The control group was treated like the test groups, except that they were
administered with 1.75ml of normal saline daily. Compared with the control
group, pueraria administration resulted in a slight decrease (P<0.05) in the
mean sperm motility, mean relative testes weight and the mean testosterone
concentration of the test groups throughout the experimental period. These
findings suggest that pueraria phaseoloides has adverse effects on sperm
parameters of male wistar rats. Pueraria phaseoloides which contain
phytoestrogens that are estrogen mimicking chemicals with estrogenic
activities might have altered the hormone receptor expression due to the
binding affinity they have for estrogen receptors α and β and androgen
receptors.",
    keywords = "male infertilty, Phytoestrogen, Female infertility, estrogen-mimicking compounds",
    author = "Kehinde Raphael Babalola",
    year = "2023",
    language = "English",
    url = "https://dapp.orvium.io/deposits/652e61ac47b4be402d9993f6/view",
}