The research examines how Information and Communication Technology (ICT) and Total Quality Management (TQM) practices affect operational efficiency in the UAE oil and gas industry. The UAE's oil and gas sector needs to enhance productivity while achieving sustainability goals because of rising global energy needs and strict environmental mandates and market risk factors. The examined effects of ICT and TQM on operational efficiency used quantitative data gathered from 100 professionals through a cross-sectional survey to conduct regression analysis. The analysis demonstrates that ICT directly and positively affects efficiency, enabled by AI, IoT, and cloud computing systems for real-time management decisions. TQM practices implementing continuous improvement, employee participation, and top management commitment yield the most powerful influence. Combined, ICT and TQM account for 75.6% of the variance in operational efficiency. Obstacles include organizational resistance to change, lack of qualified professionals, and integration challenges. The study provides essential insights for industrial leaders and policymakers to enhance the UAE’s position in the global energy market.